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HomeShopSkin CareTreatments and SerumsFace SerumsSkinMedica TNS Advanced+ Serum (1 OZ.)
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SkinMedica TNS Advanced+ Serum
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SkinMedica TNS Advanced+ Serum

SkinMedica TNS Advanced+ Serum (1 OZ.)

This Next Generation TNS Advanced+ Serum uses powerful growth factors to address signs of aging.

  • Growth factors repair and renew skin
  • Smooths fine lines and wrinkles
  • Hydrates and smooths skin
4.9 / 5.0
Read Reviews | Product FAQs | Find a Local Derm

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$295.00 Original price was: $295.00.$236.00Current price is: $236.00.

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This product: SkinMedica TNS Advanced+ Serum (1 OZ.) $236.00
SkinMedica HA5 Rejuvenating Hydrator (Multiple Sizes Available) - 2 OZ. $147.20
SkinMedica AHA/BHA Exfoliating Cleanser (6 OZ.) $38.40
SKU: S35645 Categories: Anti-Aging Treatments, Face Serums, Skin Care Tag: SkinMedica
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SkinMedica TNS Advanced+ Serum (1 OZ.)
$295.00 Original price was: $295.00.$236.00Current price is: $236.00.
View Cart Continue Shopping
Frequently Bought Together
SkinMedica HA5 Rejuvenating Hydrator (Multiple Sizes Available) - 2 OZ. $147.20 SkinMedica TNS Eye Repair (0.5 OZ.)
5.0 / 5.0
$84.80
SkinMedica AHA/BHA Exfoliating Cleanser (6 OZ.)
5.0 / 5.0
$38.40

Product Description

SkinMedica TNS Advanced+ Serum is a customer-favorite anti-aging superhero serum.

The customer-favorite SkinMedica TNS Advanced+ Serum is the next generation TNS serum. Formulated with the most advanced Growth Factor technology (TNS-MR), this intensive treatment serum supports rapid, comprehensive skin rejuvenation with significant, visible improvements in wrinkles, fine lines and overall texture. With continued use, this serum lifts the appearance of sagging skin and enhances firmness to reclaim smooth, tight and youthful-looking skin that appears up to 6 years younger after 12 weeks*. This serum has two different chambers with two separate formulas that combine to create the TNS Advanced+ Serum. These powerful blends work to rejuvenate the skin for optimal anti-aging advantages. The first chamber includes a next-generation growth factor blend. The second chamber contains a blend of botanicals, peptides, and marine extracts. Together, these formulas fight signs of aging and repair your skin.

Why DermWarehouse Loves SkinMedica TNS Advanced+ Serum:

The SkinMedica TNS collection is beloved for its anti-aging abilities. The new TNS Advanced+ serum uses revolutionary growth factors blended with peptides and botanical extracts to repair skin from the inside out. It visibly smooths fine lines and diminishes wrinkles for firmer, more youthful skin. It’s gentle and non-irritating and can be used on any skin type, whether you’re looking to prevent aging or repair it. If you’re looking for heavy-duty anti-aging help, this serum is for you.

Why Our Customers Love the SkinMedica TNS Advanced+ Serum:

Our customers have a lot of great feedback about the SkinMedica TNS Advanced+ Serum. You can read all of the reviews below, but we wanted to highlight some key points for you. SkinMedica TNS Advanced+ Serum works well for all ages and we have both women and men that use & love this product. We have customers over 80 years old who say that this serum has worked miracles for them and makes them look much younger, but the products works wonders for all ages.

Our customers consistently call this product a miracle for their skin and cannot get over the amazing results. This is a product that when customers start using, it becomes a staple in their skin care routine, many stating how they’ve used it for years and couldn’t do without it.

There are mixed feelings on the two pump system, as some customers have issues getting the product to dispense properly, but others love the dual pump system. If you ever have problems with your pump, contact our customer service team and we’ll help you get a replacement product.

Many dermatologists recommend this product to their patients and because of the stellar lineup of ingredients included, it can even replace other products in your regimen. While the product is on the more expensive side, it begins working quickly, has clinical studies to back it up, and most of our customers feel that the price is justified. It’s brightened up many of our customers’ complexions so much so that they no longer feel they need to wear foundation!

The SkinMedica TNS Advanced+ Serum reduces wrinkles, smooths skin and evens skin tone & texture, which is why it’s great for women and men in their 30’s, 40’s, 50’s and beyond. Our customers can’t believe the compliments they begin receiving about their skin and how young they look once they start using this product twice daily.

Brand Details: SkinMedica
  • Product Overview
  • Product Overview
  • Best For
  • Benefits
  • How To Use
  • Ingredients
  • Videos
  • Q&A
  • Reviews
Product Overview
SKU S35645
BrandSkinMedica
HIGHLIGHTS
  • Boosts collagen and elastin production
  • Contains probiotics
  • Helps with anti-aging efforts
  • Contains growth factors
PRODUCT TYPE
  • Anti-Aging Treatments
  • Face Serums
  • Skin Care
Product Consistency
  • Serum
Concern
  • Anti-Aging
  • Crepey Skin
  • Fine Lines & Wrinkles
  • Free Radical Damage
  • Hyperpigmentation
  • Loss of Firmness
  • Rough Skin
  • Sun Damage
  • Uneven Skin Tone
Benefits
  • Anti-Wrinkle
  • Brightening
  • Firming
  • Repairing
Skin Type
  • All Skin Types
Application Area
  • Decollete
  • Face
  • Neck
Ingredient
  • Antioxidants
  • Coenzyme Q10
  • Growth Factors
  • Peptides
Ingredient Preferences
  • Dermatologist Approved
Gender
  • Female
  • Male
Complete Your Regimen
  1. SkinMedica Facial Cleanser
  2. SkinMedica TNS Advanced+ Serum
  3. SkinMedica Dermal Repair Cream
  4. SkinMedica TNS Eye Repair
Product Overview
SKU
  • S35645
HIGHLIGHTS
  • Boosts collagen and elastin production
  • Contains probiotics
  • Helps with anti-aging efforts
  • Contains growth factors
BENEFITS
  • Anti-Wrinkle
  • Brightening
  • Firming
  • Mattifying
  • Repairing
CONCERNS
  • Anti-Aging
  • Fine Lines & Wrinkles
  • Loss of Firmness
  • Uneven Skin Tone
INGREDIENTS
  • Growth Factors
  • Peptides
INGREDIENT PREFERENCES
  • Fragrance-Free
  • Paraben-Free
PRODUCT TYPE
  • Treatments & Serums
FORMULATION
  • Serum
SKIN TYPE
  • All Skin Types
APPLICATION AREA
  • Face
SIZE
  • Carry-On Friendly
COMPLETE YOUR REGIMEN
  • SkinMedica Facial Cleanser
  • SkinMedica TNS Advanced+ Serum
  • SkinMedica Dermal Repair Cream
  • SkinMedica TNS Eye Repair
CATEGORIES
  • Anti-Aging Treatments, Face Serums, Skin Care
Best For
  • Good for all skin types
  • Best for mature skin
Benefits
  • The only growth factor proven to address sagging skin
  • Smooths the appearance of coarse wrinkles and fine lines
  • Results starting in just 2 weeks
  • Progressive results, even at 24 weeks
  • Patients felt they looked 6 years younger after 12 weeks
How To Use
  • Use AM & PM.
  • Dispense a single pump onto the back of your hand, blend together and apply to the face.
  • Avoid getting in eyes.
  • If contact occurs, rinse eyes thoroughly with water.
Ingredients

Water/Aqua/Eau, Pentylene Glycol, Human Fibroblast Conditioned Media, Glycereth-7 Triacetate, Shea Butter Ethyl Esters, Glycerin, Ethoxydiglycol, Lactococcus Ferment Lysate, Whey Protein, Chlorella Vulgaris Extract, Saccharide Isomerate, Trifluoroacetyl Tripeptide-2, Dimer Tripeptide-43, Hydrolyzed Linseed Extract, Vitis Vinifera (Grape) Flower Cell Extract, Pyrus Malus (Apple) Fruit Extract, Hydroxyacetophenone, Tocopheryl Acetate, Propanediol, Xanthan Gum, Polyacrylate Crosspolymer-6,& Polyacrylate-13, Polyisobutene, Sclerotium Gum, PEG-12 Dimethicone, Lecithin, Pullulan, Butylene Glycol, Sodium Citrate, Polysorbate 20, Aminomethyl Propanol, Dextran, Disodium EDTA, Phenoxyethanol, Ethylhexylglycerin

Videos
Q&A

When should I use TNS Advanced Serum?



This serum can be applied both morning and night and should be used after cleansing and toning but before any additional treatments or products.



What are in each of the chambers of the SkinMedica TNS Advanced+ Serum?



In chamber one of the Advanced+ is the TNS®-MR. This next-generation growth factor blend acts on multiple levels to help get the best results for your skin. This chamber contains 450 growth factors (the TNS Recovery Complex contains 380), plus peptides. Whereas you probably associate the TNS Recovery Complex with its reddish hue and very recognizable scent, the TNS®-MR is completely colorless and odorless.

In chamber two of the Advanced+ Serum is the Renessensce (RSC) Advanced. Specifically designed to support the results of the growth factor blend, this highly active blend includes botanicals, marine extracts, and peptides. It also contains probiotics, which improve barrier function and skin texture and antioxidants. The Renessensce does not contain Vitamin C, as this ingredient tends to be more irritating. TNS Advanced+ is non-comedogenic and it’s great for all skin types.



Is the SkinMedica TNS Advanced+ worth the price tag?



While the TNS Advanced+ Serum comes with a hefty $295 price tag, we can tell you that it's 100% worth the price, as it's actually two products in one. Each one of its two chambers holds an entirely different treatment and work together to deliver ultimate anti-aging benefits. This serum stimulates the skin's natural anti-aging abilities like nothing else on the market. Not only that, it drastically improves skin texture, tone, elasticity, and overall skin health. This product can replace multiple products within your routine all in one product, making it easy to get tons of skincare benefits in one. This serum teaches your skin to “think young” again and revitalizes and renews skin from the inside out.

The revolutionary formula in the  TNS Advanced+ addresses all key aging skin concerns. The formula works on all layers of the skin and also addresses prejuvenation to actually delay the onset of skin aging. This is the first time that SkinMedica is able to claim that a product improves the appearance of sagging skin. The SkinMedica TNS Advanced+ is also clinically proven to reveal results in just 14 days, with skin that appears up to 6 years younger after 12 weeks. With this product, you will see real results after just one bottle!



Do I still need to use a moisturizer with the TNS Advanced Serum?



Yes, we recommend using a moisturizer after the TNS Advanced Serum morning and night.



Can I use Vitamin C with the TNS Advanced Serum?



Yes, you can use Vitamin C alongside the TNS Advanced Serum.

Reviews
4.9 / 5 • 88 reviews
Trustpilot
1 month ago
Cheryl Norman
NO WRINKLES on my 84 year old face!
5 months ago
Cheryl Norman
My life is better because TNS SKIN MEDICA makes me look my best! Thank you Parkers for your genius products!!!
8 months ago
Cheryl Norman
Love the TNS Skin Medica. It makes me look 20 years younger than I am!!! So I can still work with my piano students & write scientific articles.
10 months ago
Cheryl Norman
Fabulous product---makes me look 20-30 years younger than my real age of 83.
11 months ago
Lynn
It is wonderful! VERY Expensive but worth it. I always wait until it is on sale.
11 months ago
tracy miller
I feel like I am seeing improved skin texture
1 year ago
Cheryl Norman
Greatest product on the market to keep my face wrinkle free! DermWarehouse is the best company with whom to do business! Thank You!
1 year ago
customer
I’ve been using this product for a while and always appreciate when it’s on sale!
1 year ago
Patricia Overholser
I swear by this product and if they quit making it I do not know what I would do. I am 80 y.,o. and people think I am in my 60's I contribute it all to this age reversing product.
1 year ago
Heidi Wood
SkinMedica is my go to face lotion. I have used this for about 2 years now. My skin is sensitive, but I don’t have any problems with this product.
1 year ago
Cheryl Norman
An incredible product that deletes the wrinkles from my face! Best price also—when compared to similar products!
1 year ago
Dianne
I really like it.
1 year ago
Cheryl Norman
Best wrinkle free facial oil on the market!
1 year ago
Christine Paton Holt
Magical serum for aging skin!
1 year ago
Cheryl Norman
AMAZING product developed by DermWarehouse. Other companies have developed similar products aren’t as effective & are much more expensive!
1 year ago
Christine Paton Holt
GREAT stUFf1
1 year ago
Lynn
It is very expensive but worth it!
1 year ago
Carol
This product works. The ingredients are products that really work. You can see a difference in your skin in 2 weeks time.
1 year ago
CynthiaM
great on my skin, it works.
2 years ago
Jean
Love the product because it makes me glow and have been using it for years. The delivery mechanism STILL needs to be fixed since it doesn’t work consistently. This has been the case for years so they really should address this. I store it upside down and it seems to help. But for the price, they need to address this!
2 years ago
N/A
Have been using it for a few weeks now and love it! I ordered another one to have when this one runs out.
2 years ago
Sandra Lauterbach
Amazing results!
2 years ago
Christine Paton Holt
Does wonders for my skin!
2 years ago
Lisa in Franklin TN
I’ve been using the TNS Advanced Serum for over a year now as part of my skin care routine and I really love it! I get compliments all the time on my skin and I feel so confident that I’ve replaced my foundation with a tinted moisturizing sunscreen.
2 years ago
Christine Paton Holt
Love this facial cream - plumps skin, moisturizes, makes skin so soft & glowy!
2 years ago
Cheryl Norman
TNS is a "miracle" skincare serum. I use it every day and although I am 82, I look much younger-because I have NO wrinkles on my face--thanks to SkinMedica TNS Advanced+ Serum! Thank you Dermwarehouse!
2 years ago
Virginiagirl
Love it- I’ve been using it for several years- really works!
2 years ago
Dottie
It makes a tremendous difference in my complexion.
2 years ago
Julie
My esthetician recommended this product to me years ago and my skin is exceptionally good for someone in their 60’s.
2 years ago
Justine Sindt
great formula, no piling, smooth
2 years ago
Kristen S
Great product. Goes on smoothly and absorbs evenly.
2 years ago
SHARON BLOCK
I might like the original product better.
2 years ago
Dawn Perlmutter
This is one of my most favorite products that I’ve ever used. It feels so amazing when you put it on your face that once you’ve tried it you will never want to be without it. I really get a lot of compliments on my skin and I use mostly Skin Medica products and have for quite some time. The only odd thing about it is that it is a mixture of 2 products that come out of the pump at the same time and one always runs out first.
2 years ago
Linda Zanyk
Very helpful as I age in keeping some of those fine lines at bay. Use it every morning and evening on my clean face.
2 years ago
Cheryl Norman
Best product ever! Everyone should use this when you see wrinkles creep onto your face!
3 years ago
CynthiaM
leaves my skin clear & soft to touch
3 years ago
Keri Aroesty
Excellent product! absolutely love this! Its great for anti-aging and relaxing fine lines and wrinkles. Highly recommend!
3 years ago
Cheryl Norman
This product helps me to look many years younger--no lines or wrinkles on the face of this 81 year old Grandma!
3 years ago
Christine Paton Holt
New to this product but seeing signs of improvement in skin already.
3 years ago
Shelley Zito
My dermatologist recommender this and I've been using it for about 3 years and what a difference it makes!
3 years ago
denise belt
Although this item is on the expensive side, Dermwarehouse offers the best price. It is well worth the money. I am an older woman and this product has really brightened my complexion and I rarely wear foundation. I highly recommend this product.
3 years ago
Muhammad Choudhry
Excellent Product. The pump always takes a few applications for me to start working perfectly for me.
3 years ago
LS
Great product but very pricey - not sure of value
3 years ago
Indy Nana
This product smoothed out small wrinkles and makes my skin feel smooth. It is an indulgence but worth it to me.
3 years ago
Theresa Kamen
This stuff really works! I get so many compliments on my skin!
3 years ago
Maureen Markus
Love this serum!Have been a fan for years.Especially love the new advanced version.Tried many others but always come back to this one.
3 years ago
Karen
I have been using this serum for about 1 year. I felt it was working well, but based on the price, I was starting to reconsider. The test came! We were traveling for a full month. Because the serum is activated when pumped together, you cannot prepump into a smaller container. The packaging was too big to bring. To my surprise, by the end of that month on our return, I noticed a significant difference. I immediately went back to using the serum! Yes, it is expensive, but it does work. I prefer this over injectables.
3 years ago
Cheryl Norman
SkinMedica TNS advanced Serum is AMAZING! I have used this outstanding product for 10 years. I am 81 years old & have no facial wrinkles—so I look much younger!! And I continue to teach Piano Lessons at my age. I eat a healthy diet so that I have the energy of a younger person!! Thank you DERMWAREHOUSE for this Wonderful Product that keeps me Young!! I am the White hair lady in the photos.
3 years ago
Rachel A. Poirier
Love love this serum and although pricey very well worth it - my skin radiates!
3 years ago
Kristen S
The texture and tone of my skin has improved dramatically!
3 years ago
Lynne Greenberg
Fabulous!!!!
3 years ago
lalulu
Great stuff. Can't be without it. I love this with the SkinMedica Dermal Repair moisturizer layered over it. The results are subtle but over time it pays off.
3 years ago
Dianne
I feel very comfortable using this product. I am satisfied with the result and feel it is worth the cost.
3 years ago
Cheryl Norman
Thank you for taking the bad jar back and replacing it with a new jar! Love your products!
3 years ago
Sandra Lauterbach
Worth every drop!
3 years ago
Jeanne bowman
I was excited to try Skinmedica Advanced because being 67 yrs I could use the help.I started seeing results after the first 2wks but I also developed a small rash on my cheeks.I use it now only in the evenings which may not be enough.I think there is retinol in the product which I have had trouble with in the past.anyway the product works! My kids have noticed.maybe every other day would be better.
3 years ago
BA
Helps with fine lines and any blemish that is starting to form.
3 years ago
Linda Grammer
Great Product
3 years ago
Kim Arino-Lacock
Feels good going on. Not sure I see such a big change in my skin and so was expecting. Although I was only using once per day not twice.
3 years ago
Linda Smith
This product is wonderful . It makes your skin feel so soft and hydrated. It also improves the looks of lines and wrinkles .
3 years ago
Janice Glaser-silverstone
Great service
3 years ago
L. M.
Excellent product. This is my 4th order and highly recommend.
3 years ago
Cheryl Norman
Fabulous Product--Everyone over 50 needs to use this product daily on their face! I am 80 in the picture below.
4 years ago
Julie
Can’t live without!
4 years ago
Paula Carrico
Great product. Have been using for years. Now there is "new, improved" and it is even better!
4 years ago
Juliette
Love this stuff
4 years ago
Cheryl Norman
This is the best eraser of facial lines on the market. I am 80 years old and most people don't believe me when I tell them my age---all because I put SkinMedica TNS ADvanced+ Serum on my face each day. I have been using your products for about 15 years. Thank you for helping me stay "young". . .
4 years ago
Dana
This really does make a difference with reducing lines and the puffiness one starts to acquire if over a certain age. Makes me looks 10 years younger - love it and will never buy anything else~! I tried this upon the recommendation of a dermatologist and am very thankful for the direction as there are just too many products out there. This one really works!
4 years ago
Diane Mueller
The best product I have ever used. My skin is brighter, softer and firmer. I will not use another product line. I am sold on SkinMedica
4 years ago
Punardeep Chhabra
Great serum. Absorbs well, and definitely delivers. Similar in feel/texture to the older TNS serum, but the formula are color are both different.
4 years ago
lalulu
I love everything SkinMedica. Their TNS line is the best. This is the newest anti aging product in their line and I have high hopes.
4 years ago
Rachel A. Poirier
Although a bit pricey, I am totally addicted and love the SkinMedica Advanced +Serum. I use several SkinMedica products and love all of them! Thank you to Stephanie for this new product comparison video that I found very helpful!
4 years ago
Patricia Coyne-Johnson
Another great product from SkinMedical. Well worth the price.
4 years ago
Linda Smith
It is wonderful . My face glows and feels so soft . It gives you a refreshed look.
4 years ago
bostongirl
Love this new product and use daily!
4 years ago
MN
Just a great product
4 years ago
Dianne Hammond
Just started using this but so far I love it!
4 years ago
Linda Smith
I liked the way it makes face soft and glows
4 years ago
Julie A Loewenstine
Product even better now in this new advanced formula..even when I thought couldn’t get any better!
4 years ago
Amy Hartman
Makes my skin smoother and younger looking.
4 years ago
Randi Realson
love this serum!
4 years ago
Billie Shapiro
I’ve used this product for a number of years and don’t see a huge difference in my skin. But I continue to use it because if I stop my skin might get worse . I do use it in conjunction with RetinA
4 years ago
Andrea
Love it! Visible improvement.
4 years ago
KK
Amazing stuff! Didn't think they could improve on the original version, but they did.
4 years ago
Amy Hartman
Leaves my skin smooth and hydrated. Small wrinkles are less apparent.
4 years ago
Barb Rodas
Goes on very well and soaks in. I hope it reduces sagging like it says it does.
4 years ago
Patricia Coyne-Johnson
Great product.
4 years ago
Rachel A. Poirier
I am a true fan of Skin Medica products!

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    A deeply moisturizing treatment for normal to dry skin that helps to reduce the overall signs of aging.
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    Clinicians Complex Bruise Cream (2 OZ.)

    4.0 / 5.0
    $70.00
    A cream to reduce bruising associated with cosmetic surgery procedures.
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    Clinicians Complex Facial Toner (7.5 OZ.)

    4.5 / 5.0
    $35.00
    A non-irritating, alcohol-free and oil-free toner.
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    Clinicians Complex Facial Cleanser (7.5 OZ.)

    $39.00
    An exfoliating glycolic acid based anti-aging facial cleanser for normal to dry skin.
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